Henry Grey, 2nd Earl of Tankerville, 7th Lord of Powys (c. 1418/c. 1419 – 13 January 1449/1450) was an English peer. He was the son of John Grey, 1st Earl of Tankerville and his wife Joan Charleton, co-heiress and 6th Lady of Powys.
He became the 2nd Earl of Tankerville on 22 March 1420/1421 and was invested as a Knight in 1426.
Tankerville had Sir Gruffudd Vychan summarily executed in Powis Castle in 1447, in violation of a safe conduct given. It is not known whether he suspected Vychan of Yorkist sympathies, whether it was in retribution for the death of Sir Christopher Talbot at Sir Gruffydd's hand, or whether he wished to eliminate Vychan's claim to Powis.
He married Antigone Plantagenet, legitimized daughter of Humphrey of Lancaster, 1st Duke of Gloucester. By her he had three children: