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Heng Li

Heng Li
Institutions Wellcome Trust Sanger Institute
Broad Institute
Beijing Genomics Institute
Thesis Constructing the TreeFam database (2006)
Doctoral advisor Wei-Mou Zheng
Known for Bioinformatics
Burrows–Wheeler transform
Samtools
TreeFam
Notable awards Benjamin Franklin Award (Bioinformatics) (2012)
Website
lh3lh3.users.sourceforge.net

Heng Li is a Chinese bioinformatics research scientist currently working at the Broad Institute in Cambridge, Massachusetts with David Reich and David Altshuler. Li's work has made several important contributions in the field of next generation sequencing.

Li majored in physics at Nanjing University during 1997-2001. He received his PhD from the Institute of Theoretical Physics at the Chinese Academy of Sciences in 2006. His thesis, titled "Constructing the TreeFam database", was supervised by Wei-Mou Zheng.

Li was involved in a number of projects while working at the Beijing Genomics Institute from 2002 to 2006. These included studying rice finishing,silkworm sequencing, and genetic variation in chickens.

From 2006 to 2009, Li worked on a postdoctoral research fellowship with Richard M. Durbin at the Wellcome Trust Sanger Institute. During this time, Li made several important contributions to the field of next generation sequencing (NGS) through the development of software such as the SAMtools NGS utilities, the Burrows–Wheeler aligner (BWA), MAQ, TreeSoft and TreeFam.

Li joined the Broad Institute in 2009, working in the core faculty lab of David Altshuler, which investigates the discovery and understanding of the genetic causes of disease.

As of April 2015, Li's papers on SAMtools and BWA (sequence alignment using the Burrows-Wheeler transform) have both been cited over 5,000 times.


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