Hemangioendothelioma

Hemangioendothelioma
Micrograph of a kaposiform hemangioendothelioma with "glomeruloid" nodules of endothelial cells.
Classification and external resources
ICD-O	9130-9133
DiseasesDB	33472
MeSH	D006390
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Hemangioendothelioma is used to describe a group of vascular neoplasms that may be considered benign as well as malignant, depending on the specific group member's activity.

Hemangioendotheliomas may be classified as:

Low power photomicrograph of an endovascular papillary angioendothelioma showing with hyalinized cores

High power view showing a vascular tumor with cuboidal endothelium lining the vessels. Few entrapped seminiferous tubules are also noted (arrow).

Characteristic budding, hobnail-like endothelial cells visible.

They have been described as masses that fall between a hemangioma and angiosarcoma. They are vascular tumors that commonly present with an enlarging mass and most commonly involve the lungs, liver, and musculoskeletal system, although many other body sites have been reported, including the head and neck, intestines, lymph nodes, pleura, retroperitoneum, heel, stomach.

Treatment is varied and depends on the site and extent of tumor involvement, site(s) of metastasis, and specific individual factors. Surgical resection, radiotherapy, and chemotherapy have all been used to treat these masses, although studies on survival have yet to be conducted to delineate various treatment regimens.

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