Heads of government of the Central African Republic and Central African Empire

Prime Minister of the Central African Republic
Coat of arms of the Central African Republic
Incumbent Simplice Sarandji since 2 April 2016
Appointer	Faustin-Archange Touadéra, as President of the Central African Republic
Inaugural holder	David Dacko
Formation	13 August 1960

The following is a complete list of heads of government of the Central African Republic and the Central African Empire. There have been twenty-three heads of government in the history of the Central African Republic and the Central African Empire since independence was obtained from the French on 13 August 1960.

The current Prime Minister of the Central African Republic is Simplice Sarandji, since 2 April 2016.

For heads of government with multiple affiliations, the political party listed first is the party the person was affiliated with at the beginning of the tenure.