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Haplogroup O1

Haplogroup O-M119
Possible time of origin 33,103 [95% CI 24,460 <-> 40,854] years ago (Karmin 2015)

34,100 or 29,200 years ago (Poznik 2016)

30,100 [95% CI 27,800 <-> 32,400] years before present (YFull 2017)
Possible place of origin Southeast Asia or Southern China
Coalescence age 16,538 [95% CI 11,755 <-> 21,147] years ago (Karmin 2015)

15,000 [95% CI 13,200 <-> 16,900] years before present (YFull 2017)
Ancestor O-M175 > O-F265
Defining mutations M119

In human genetics, Haplogroup O-M119 is a Y-chromosome DNA haplogroup. Haplogroup O-M119 is a descendant branch of O-F265, one of two extant primary subclades of Haplogroup O-M175. The same clade previously has been labeled as O-MSY2.2.

The Haplogroup O-M119 branch is believed to have evolved during the (Upper Paleolithic) in Southeast Asia.

A 2010 study by Karafet suggests haplogroup O-M119 was part of a four-phase colonization model in which Paleolithic migrations of hunter-gatherers shaped the primary structure of current Y-Chromosome diversity of Maritime Southeast Asia. Neolithic incursions made only a minor impact on the paternal gene pool, despite the large cultural impact of the Austronesian expansion. Approximately 5000 BCE, Haplogroup O-M119 coalesced at Sundaland and migrated northwards to as far as Taiwan, where O-M50 constitutes some 90% of the Aboriginal Y-DNA, being the main haplogroup that can be directly linked to the Austronesian expansion in phase 3 (Karafet 2010).

A study by Li in 2008 concluded that in contrast to the Taiwan homeland hypothesis, Island Southeast Asians do not have a Taiwan origin based on their paternal lineages. According to their results, lineages within Maritime Southeast Asia did not originate from Taiwanese aborigines as linguistic studies suggest. Taiwan aborigines and Indonesians were likely to have been derived from the Tai–Kadai-speaking populations based on their paternal lineages, and thereafter evolved independently of each other (Li 2008).

The strongest positive correlation between Haplogroup O-M119 and ethno-linguistic affiliation is that which is observed between this haplogroup and the Austronesians. The peak frequency of Haplogroup O-M119 is found among the aborigines of Taiwan, precisely the region from which linguists have hypothesized that the Austronesian language family originated. A slightly weaker correlation is observed between Haplogroup O-M119 and the Han Chinese populations of southern China, as well as between this haplogroup and the Tai–Kadai-speaking populations of southern China and Southeast Asia. The distribution of Tai–Kadai languages in Thailand and other parts of Southeast Asia outside of China has long been believed, for reasons of traditional linguistic geography, to reflect a recent invasion of Southeast Asia by Tai–Kadai-speaking populations originating from southeastern China, and the somewhat elevated frequency of Haplogroup O-M119 among the Tai–Kadai populations, coupled with a high frequency of Haplogroup O-M95, which is a genetic characteristic of the Austroasiatic-speaking peoples of Southeast Asia, suggests that the genetic signature of the Tai–Kadai peoples' affinity with populations of southeastern China has been weakened due to extensive assimilation of the earlier Austroasiatic residents of the lands which the Tai–Kadai peoples invaded. Also, it has been noted that Haplogroup O-M119 lineages among populations of continental Southeast Asia outside of China display a reduced level of diversity when compared with populations of South China and insular Southeast Asia, which may be evidence of a bottleneck associated with the westward migration and settlement of ancestral Tai–Kadai-speaking populations in Indochina.


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