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Guy Henry Faget

Guy Henry Faget
Born 1891
America
Died 1947
Nationality America
Occupation Physician, Director of a leper hospital at Carville, America
Known for Discovery of the effectiveness of promin in the treatment of leprosy in 1943

Guy Henry Faget (1891–1947) was an American doctor who revolutionalized the treatment of leprosy by demonstrating the efficacy of promin, in a paper reported in 1943. Promin is a sulfone compound synthesized by Feldman and his co-workers in 1940 as an agent against tuberculosis effective in experimental animals. He was the grandson of Jean Charles Faget, and father of Maxime Faget.

For 25 years he was a distinguished officer of the US Public Health Service. In 1940 he became the director of the United States Marine Hospital (National Leprosarium) at Carville, Louisiana, United States of America. He was a member of the International Leprosy Association (ILA) and a consultant to the Advisory Medical Board of LWM. He died in a fall after having heart disease in 1947.

On May 7 to 9, 1942, he was invited to the 44th Annual Meeting of the Medical Library Association, New Orleans, and read a paper. In this paper he described the present situation of leprosy in the United States, and the National Leprosarium at Carville with photographs. He hinted important progress would be made in the near future.

This is the paper written immediately before the promin paper. Toxic effects of this drug were considerable, but among 20 cases, it was effective in 6, and another 2 were also effective but on their road to improvement. One case remained unchanged and 10 cases progressed. In its conclusions, they clearly wrote that sulfanilamide cannot be regarded as a curative agent for leprous lesions, either of the macular or lepromatous type.


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