The Gulfport-Biloxi-Pascagoula Combined Statistical Area is made up of five counties in the Mississippi Gulf Coast region. The statistical area consists of the Gulfport-Biloxi Metropolitan Statistical Area and the Pascagoula Metropolitan Statistical Area. As of the 2000 census, the CSA had a population of 396,754. The area was significantly impacted by Hurricane Katrina in 2005. As of the 2010 Census the estimate placed the population at 411,066 and as of 2014 the estimated population was 427,322.
As of the census of 2000, there were 396,754 people, 147,600 households, and 105,041 families residing within the CSA. The racial makeup of the CSA was 76.72% White, 18.82% African American, 0.41% Native American, 1.87% Asian, 0.06% Pacific Islander, 0.75% from other races, and 1.37% from two or more races. Hispanic or Latino of any race were 2.26% of the population.
There were 147,600 households out of which 34.8% had children under the age of 18 living with them, 52.3% were married couples living together, 14.2% had a female householder with no husband present, and 28.8% were non-families. 23.6% of all households were made up of individuals and 8.1% had someone living alone who was 65 years of age or older. The average household size was 2.66 and the average family size was 3.10.