Guanabenz

Guanabenz
Clinical data


AHFS/Drugs.com	Consumer Drug Information
MedlinePlus	a686003
Pregnancy category	US: C (Risk not ruled out)
ATC code	none
Pharmacokinetic data
Protein binding	90%
Biological half-life	6 hours
Identifiers
IUPAC name 2-(2,6-dichlorobenzylidene)hydrazinecarboximidamide
CAS Number	5051-62-7
PubChem CID	5702063
IUPHAR/BPS	5443
DrugBank	DB00629^Y
ChemSpider	4642445^Y
UNII	GGD30112WC
KEGG	D04375^Y
ChEMBL	CHEMBL420^Y
ECHA InfoCard	100.023.410
Chemical and physical data
Formula	C₈H₈Cl₂N₄
Molar mass	231.081 g/mol
3D model (Jmol)	Interactive image
SMILES Clc1cccc(Cl)c1\C=N\N=C(/N)N
InChI InChI=1S/C8H8Cl2N4/c9-6-2-1-3-7(10)5(6)4-13-14-8(11)12/h1-4H,(H4,11,12,14)/b13-4+^Y Key:WDZVGELJXXEGPV-YIXHJXPBSA-N^Y

Guanabenz (pronounced GWAHN-a-benz, sold under the trade name Wytensin) is an alpha agonist of the alpha-2 adrenergic receptor that is used as an antihypertensive drug. It is used to treat high blood pressure (hypertension).

The most common side effects during guanabenz therapy are dizziness, drowsiness, dry mouth, headache and weakness.

Guanabenz can make one drowsy or less alert, therefore driving or operating dangerous machinery is not recommended.