Groundplasm is the submicroscopic ground cell substance or cytoplasmatic matrix which remains after exclusion of the cell organelles and other particles. It is the "hyaloplasm" of light microscopy, and the high-complex, polyphasic system in which all of the resolvable cytoplasmic elements are suspended, including the larger organelles such the ribosomes, , the plant plastids, lipid droplets, and vacuoles.
Groundplasm contains most of the intermediate enzymes of cell metabolism, including those involved in preliminary or alternative pathways of ATP synthesis. It holds the metabolic cell reserves and the main cellular pool of soluble precursors. It also contains the contractile protein molecules responsible for most cell contractions and movements.