Gregorio Elso Pérez Perdigón (born 16 January 1948 in Maldonado) is a retired Uruguayan footballer. He now works as a manager. He is widely reputed in his country due for his respectful approach toward the game and general sportsmanship. He is known as "Don Gregorio".
Gregorio Perez also acted as an assistant manager to Oscar Tabarez during the Uruguayan national football team's 1990 Football World Cup campaign.