The Great Mosque of Niono is an architecturally significant mosque located in the city of Niono, in the Ségou Region of southern Mali.
The mosque was first constructed in 1948 by a team of bricklayers native to Djenne, and it today occupies 1,800 square meters. It is perhaps the most internationally recognized site in the town of Niono, having received the Aga Khan Award for Architecture in 1983.
This site was added to the UNESCO World Heritage Tentative List on March 19, 2008 in the Cultural category.