Great Marlborough Street is a thoroughfare in Soho, Central London. It runs east of Regent Street past Carnaby Street towards Noel Street.
Originally part of the Millfield estate south of Tyburn Road (now Oxford Street), the street was named after John Churchill, 1st Duke of Marlborough and was laid out around 1704. It was a fashionable address in the 18th century, but its character changed to commercial and retail use by the end of the 19th. Most of the street's original buildings have since been demolished. Great Marlborough Street has had an association with the law since the late-18th century; Marlborough Street Magistrates Court subsequently became one of the most important magistrates courts in London. The department store Liberty is on the corner of Great Marlborough Street with Regent Street and sports a Mock Tudor facade.
The road is about 0.2 miles (0.32 km) long. At its western end it joins Regent Street and runs east, crossing Kingly Street, Argyll Street, Carnaby Street, and Poland Street. At its eastern end, it becomes Noel Street.
The nearest tube station is Oxford Circus to the northwest. No buses run along Great Marlborough Street but there are numerous services on Regent Street.
In the 16th century, what is now Great Marlborough Street was land belonging to the Mercer's Company. It was surrendered to Henry VIII in 1536. The land was subsequently owned by local brewer Thomas Wilson. His son, Richard, inherited this in 1622 who sold it to William Maddox, who called the estate Millfield. In 1670, Maddox's son, Benjamin, let the land to James Kendrick for 72 years, who in turn sub-let what is now Great Marlborough Street to John Steele. The land remained undeveloped, with building focusing on Tyburn Road (now Oxford Street) to the north.