Gray Drug was a drugstore chain in Cleveland, Ohio. The chain began in 1912 and grew to 46 stores by 1946 and over 100 by the 1970s. Besides Ohio, stores later opened in Florida and Maryland. The chain later acquired Drug Fair in 1981, shortly before Sherwin Williams bought the chain. Gray Drug acquired several Cunningham Drug stores in 1982.
The company entered the discount department store business by acquiring the Cincinnati-based Rink's Department Store chain in 1964 and the Cleveland-based Bargain City chain in 1967. and merged Bargain City into Rink's. Sold the combined Rink's chain to Cook United in 1981.
Gray Drug was sold to Rite Aid in 1987.