There are 236 Grade II* listed buildings in Greater Manchester, England. In the United Kingdom, the term listed building refers to a building or other structure officially designated as being of special architectural, historical or cultural significance; Grade II* structures are those considered to be "particularly significant buildings of more than local interest". In England, the authority for listing under the Planning (Listed Buildings and Conservation Areas) Act 1990 rests with English Heritage, a non-departmental public body sponsored by the Department for Culture, Media and Sport.
The metropolitan county of Greater Manchester is made up of 10 metropolitan boroughs: Bolton, Bury, Manchester, Oldham, Rochdale, Salford, , Tameside, Trafford and Wigan. The Grade II* buildings in each borough are listed separately. Manchester, the world's first industrialised city, has 77 of Greater Manchester's 238 Grade II* listed buildings, the highest number of any borough. Bury has the least, with only eight. The River Irwell forms the boundary between Salford and Trafford, so one listed structure, Barton Swing Aqueduct, has been listed under both Salford and Trafford.