For historical reasons, the post office in Goldsboro is named "Etters" even though there is no incorporated place known by that name, and the USPS states that the name "Etters" is preferred over "Goldsboro" for addressing mail to ZIP code 17319. (See § History, below.)

The Goldsboro Historic District was listed on the National Register of Historic Places in 1984.

The name "Etters", used by the USPS to refer to the post office in Goldsboro, comes from the establishment in 1838 of a post office inside a tavern owned by Henry Etter, a former Revolutionary War soldier, about a mile north of the current location of Goldsboro. The post office was moved to Goldsboro in 1850, at which time it retained the name "Etter's" to avoid confusion with the already established post office in Gouldsboro, Wayne County, PA.

Goldsboro is located along the Susquehanna River and has a view of the Three Mile Island Nuclear Generating Station, the site of the largest nuclear accident in the United States.

As of the census of 2000, there were 939 people, 333 households, and 260 families residing in the borough. The population density was 2,306.3 people per square mile (884.3/km²). There were 365 housing units at an average density of 896.5 per square mile (343.7/km²). The racial makeup of the borough was 98.51% White, 0.21% Native American, 0.53% Asian, 0.11% Pacific Islander, and 0.64% from two or more races. Hispanic or Latino of any race were 0.64% of the population.

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