"Go! Go! Let's Go!" is a song recorded and performed by Japanese collective unit E-girls, taken as a single from their fourth studio record E.G. Crazy (2017). The track was released on November 30, 2016 through Rhythm Zone and Avex Music Creative Inc. in three physical formats—two CD's and a DVD bundle—and for digital consumption. The song was written by Kotake Masato, composed by Lisa Desmond, Erik Lidbom and Maria Marcus, and produced by Exile's Hiro. It is the final single to feature Dream member Erie Abe, whom left the band on December 31 that same year.

"Go! Go! Let's Go!" serves as the opening entry for their Japanese Neo Girls concept, which utilizes different cultures from a Japanese women's perspective. Musically, it is a dance number that incorporates elements of hip-hop and rock music, and delves into themes of being ambitious and moving on. Additionally, the physical and digital packaging included the B-side "Bon Voyage", which was included on the parent album. "Go! Go! Let's Go!" features all remaining vocalists members from the group. Upon its release, "Go! Go! Let's Go!" received positive reviews from music critics, who commended the tracks mixture of genres and production, with compliments aimed towards their incorporation of the Japanese Neo Girls concept.

Commercially, it experienced minor success in Japan, peaking at number two on the Oricon Singles Chart and on the Japan Hot 100, the latter published by Billboard, but selling fewer copies than their previous releases. In order to promote the single, E-girls performed in the accompanying music video, which was directed by Daisuke Ninomaya, and features the band exemplifying the respective concept into the visual; for example, the girls utilize various Japanese cultures. Additionally, the girls sung and performed the track on several shows.

After releasing their "summer concept" singles "E.G. Summer Rider" (July 2016) and "Pink Champagne" (August 2016), E-girls continued recording material for their fourth studio album, E.G. Crazy (2017). On October 20 that year, the band announced through their website about the release of "Go! Go! Let's Go!", and confirmed its pre-order availability that same day. Details were still unavailable at the time, but revealed the three accommodating formats for the single. Additionally, this is the last single to feature Dream member Erie Abe, whom announced her retirement in October from both E-girls and Dream, and the entertainment industry as a whole, by the end of the year; on December 31, Abe committed to her promise and left the bands.

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