Giuseppe Arzilli (born February 20, 1941 in San Marino) is a Sammarinese politician, and was formerly the Captain Regent San Marino.
He served three six-month terms, the first from October 1986 to April 1987, the second from October 1999 to April 2000, and the third from October 2004 to April 2005. He is a member of the Sammarinese Christian Democratic Party.