Giovanni Borgia, 2nd Duke of Gandia

Giovanni Borgia
Duke of Gandia
Alleged portrait of Giovanni Borgia
Reign	1488-1497
Spouse(s)	Maria Enriquez de Luna
Issue Juan de Borja y Enriquez, 3rd Duke of Gandia Francisca Jesus de Borja Isabel de Borja y Enriquez
Noble family	House of Borgia
Father	Pope Alexander VI
Mother	Vannozza dei Cattanei
Born	c1476 Italy
Died	14 June 1497 Rome
Religion	Roman Catholicism

Giovanni Borgia, 2nd Duke of Gandía (1474 or 1476–1497) was the son of Pope Alexander VI a member of the House of Borgia who was murdered in 1497. He was the brother of Cesare, Gioffre, and Lucrezia Borgia. Giovanni, commonly known as Juan (or sometimes, Joan), is believed to be the eldest of the Pope's four children by Vannozza dei Cattanei, but this is disputed. Due to the contents of a number of papal bulls issued after his murder, it is unclear whether Giovanni was born in 1476 or 1477.

Giovanni Borgia was probably born in Rome to then-cardinal Rodrigo Borgia (later to become Pope Alexander VI), and his mistress, Vannozza dei Cattanei, who was married to Domenico da Rignano. Giovanni married Maria Enriquez de Luna, the Spanish betrothed of his deceased older half-brother, Pedro Luis, in September 1493. He was made 2nd Duke of Gandia, Duke of Sessa, Grand Constable of Naples, Governor of St. Peter's, and Gonfalonier and Captain General of the Church.

Giovanni and Maria had three children: twins Juan de Borja y Enríquez (known as Juan Borgia, father of Francis Borgia, 4th Duke of Gandía), who became the 3rd Duke of Gandía, and Francisca de Jesús Borja, who became a nun at a convent in Valladolid. The younger Juan was the father of Saint Francis Borgia. Their third child, Isabel de Borja y Enríquez, was born after her father was killed; she grew up to be abbess of Santa Clara in Gandia.