Gilbert Clerke (1626–c.1697) was an English mathematician, natural philosopher and Socinian theological writer.
Born at Uppingham, Rutland, in 1626, he was a son of John Clerke, master of the school there. In 1641 he was admitted to Sidney Sussex College, Cambridge, and there he proceeded M.A., being elected a fellow in 1648. In 1651 he received presbyterian ordination; he became proctor also in the next year, 1652; but in 1655 he resigned his fellowship and left the university, because the statutes required him to take the degree of Bachelor of Divinity, and his conscientious scruples made this impossible.
His ability brought him into communication with Richard Cumberland, his contemporary at Cambridge, and with William Whiston; but, inheriting a small property at Luffingham, Northamptonshire, he quietly pursued his mathematical studies in that county to the end of his life. He did approach Isaac Newton for some clarification of the Principia. His directions to find the meridian relate to observations taken at Stamford, where Whiston knew him. He laid out the gardens of Lamport Hall.
The manner and the time of his death are not recorded. He is supposed to have died about 1697.
In 1660 he issued his first work, De Plenitudine Mundi. In this he reviewed René Descartes and attacked Francis Bacon, Thomas Hobbes, and Seth Ward. In the next year he was following the lines of Torricelli and Robert Boyle; and, dedicating the resulting work to Sir Justinian Isham, he brought it out in 1662 as Tractatus de Restitutione Corporum, which replied to Francis Line. Another work of his was Finalis Concordia, alluded to by him in some correspondence with Richard Baxter on church divisions.