Giacomo Antonio Francesco Paolo Michele Insanguine (22 March 1728, Monopoli – 1 February 1793, Naples) was an Italian composer, organist, and music educator. He was the last director (primo maestro) of the conservatoire of Sant'Onofrio in Naples, which merged in 1795, two years after Insanguine's death, with the conservatoire of Santa Maria di Loreto.