In 1990, producers Phil Wilde and Jean-Paul de Coster had previously gained success with AB Logic, and were looking for another vehicle for their songs. 2 Unlimited formed when Wilde and DeCoster were introduced to rapper Ray Slijngaard and vocalist Anita Doth by Marvin D., who had featured both in his rap group in the past.

"Get Ready for This" was released in September 1991 as the lead single from 2 Unlimited's debut album Get Ready! Originally, the single was produced as an instrumental, titled the "Orchestral Mix". Conscious of their popularity, Wilde & De Coster wanted a more accessible, formatted formula for their project to grow. Ray was then asked to write lyrics and add a rap to the track. On Ray's suggestion, Anita joined as the female vocalist.

The rap version was released with raps by Ray Slijngaard and vocals by Anita Doth. For the UK release of the single, an edit of the original "Orchestral Mix" was used, without vocals except for the line "Y'all ready for this?" This was sampled from The D.O.C.'s hit single "It's Funky Enough." This was done by record producer Pete Waterman, who owned the record label 2 Unlimited were licensed to for UK releases.

"Get Ready for This" was an immediate success throughout Europe with notable peaks worldwide, including Australia and the U.S. It is arguably the most famous of the band's singles in the United States having charted at no. 14 on the US Billboard Hot Dance Club Play chart, no. 17 on the Top 40 Mainstream and no. 38 on the Billboard Hot 100, making it the band's only Top 40 hit in the U.S.

The song is one of the most frequently played songs at sporting events around the world, and was the opening song for the Green Bay Packers in Super Bowl XLV, and similarly served as the opening song at one time for two NBA teams, the Orlando Magic and the San Antonio Spurs. It has also been the opening song for several Major League Baseball teams, including the Cleveland Indians, Colorado Rockies, Houston Astros, Miami Marlins, New York Yankees, Philadelphia Phillies, Pittsburgh Pirates and San Diego Padres, as well as the Montreal Canadiens and San Jose Sharks of the NHL. It has also been the goal song at one time or another for two other NHL teams, the Detroit Red Wings and Toronto Maple Leafs. The Sharks currently have this song as their goal song as of late March 2016.

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