George Vicesimus Wigram (28 March 1805 – 1 February 1879) was an English biblical scholar and theologian.
He was the 20th child (hence his middle name) of Sir Robert Wigram, 1st Baronet, a famous and wealthy merchant, and the 14th child of Lady Eleanor Wigram, Robert's 2nd wife (an aunt to Charles Stewart Parnell). His family were all capable and several of his siblings became illustrious in their own field. Sir James Wigram became a judge and Vice-Chancellor; Joseph Cotton Wigram became Bishop of Rochester, Loftus Wigram was a barrister and politician, and Octavius Wigram was prominent as an insurance underwriter in the City of London.
As a young man George Wigram obtained a commission in the army. One of his postings was to Brussels. He spent an evening exploring the Waterloo battlefield and it was here he had a religious experience that changed his life. He wrote of it thus, "suddenly there came on my soul a something I had never known before. It was as if some One, Infinite and Almighty, knowing everything, full of the deepest, tenderest interest in myself, though utterly and entirely abhorring everything in, and connected with me, made known to me that He pitied and loved myself". This led to his resigning his commission in the army and in 1826 he entered Queens College, Oxford, with the intention of becoming an Anglican clergyman.
At Oxford he met John Nelson Darby and Benjamin Wills Newton. Dissatisfied with the established church, Wigram and his friends left the Anglican church and helped establish non-denominational assemblies which became known as the Plymouth Brethren. He had considered joining Anthony Norris Groves and his mission to Baghdad in June 1829, but changed his mind just prior to the faith mission set off. After leaving Oxford University, Wigram, using his family wealth, in 1831 bought church premises in Plymouth and there established a Brethren assembly. During the 1830s Wigram also financed the establishment of assemblies in London.