George Sisler Jr. (1917 – December 31, 2006) was an American general manager of three Minor League Baseball teams (the Columbus Red Birds, Rochester Red Wings and Columbus Clippers) and served as the president of the International League from 1966 to 1976. Four times he won the International League Executive of the Year award. He was the son of National Baseball Hall of Fame first baseman George Sisler. In 1989 he was presented with the King of Baseball award given by Minor League Baseball.
He had Alzheimer's disease when he died. The year after his death, he was one of the first two new inductees to the resurrected International League Hall of Fame, which had had no new members since 1963.