Major General Sir George Alexander William Leith, the second Baronet, (1775), K.C.B. O.B was the first Lieutenant-Governor of Prince of Wales' Island (Penang Island), taking the reins over from George Caunter, a magistrate who was acting superintendent following the resignation and departure of the last governor, Superintendent Major Forbes Ross MacDonald. He served in that position from his arrival in 1800 until 1803.
He was appointed an ensign in the 88th Foot in 1779 and served in Jamaica. He was promoted to lieutenant in 1780. He returned to England in November 1781 and moved to the 2nd Battalion of the Royals. He transferred to the 71st Foot in Madras in 1786. In 1789 he was appointed brigade-major and served under Major-General Sir William Meadows and Governor of India, Lord Cornwallis. He was at the sieges of Bangalore and Sevendroog, the Storming of Tippoo's lines and the surrender of Seringapatam. He was promoted to Captain-Lieutenant 74th Foot on 1 November 1792 and then to captain in the 73rd on 7 March 1795.
He served as aide-de-camp to the Governor-General in 1793 and as brigade major to the King's troops in Bengal in 1794.
In 1797 he sailed on the projected Manila expedition.
In February 1800 he was appointed Governor of Prince of Wales' Island and invested with the whole civil and military authority and on 20 April he arrived and took charge of the government. The Governor-general in council had selected him for the office of lieutenant-governor from his personal knowledge of Sir George's integrity, prudence and firmness and by his lordship's conviction that the services of Sir George Leith would be eminently useful in securing to the company all advantages to be derived from the important settlements (on Prince of Wales' Island). That year Sir George negotiated a further treaty with the Sultan for the cession of a strip of mainland Kedah which was then renamed Province Wellesley after Richard Wellesley, 1st Marquess Wellesley, the Governor-General of India. He continued to govern till 1803 when he was succeeded by Sir Robert Townsend Farquhar. The Prince of Wales' Island, together with Province Wellesley now formed the Settlement of Penang (the island having been locally known as Pulau Pinang, where in the Malay language "pulau" means "island" and "pinang" is the name of a variety of local palm tree).