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Gammaretrovirus

Gammaretrovirus
Virus classification
Group: Group VI (ssRNA-RT)
Order: Unassigned
Family: Retroviridae
Subfamily: Orthoretrovirinae
Genus: Gammaretrovirus
Type species
Murine leukemia virus
species

Mammalian virus group

Feline leukemia virus
Gibbon ape leukemia virus
Guinea pig type-C oncovirus
Porcine type-C oncovirus
Murine leukemia virus
Woolly monkey sarcoma virus

Reptilian virus group

Viper retrovirus

Avian (Reticuloendotheliosis) virus group

Chick syncytial virus
Reticuloendotheliosis virus
Spleen necrosis virus

(Human) recombinant virus group

Xenotropic murine leukemia virus-related virus

Mammalian virus group

Reptilian virus group

Avian (Reticuloendotheliosis) virus group

(Human) recombinant virus group

A gammaretrovirus is a genus of the retroviridae family. Example species are the murine leukemia virus and the feline leukemia virus. They cause various sarcomas, leukemias and immune deficiencies in mammals, reptiles and birds.

Many endogenous retroviruses, closely related to exogenous gammaretroviruses, are present in the DNA of mammals (including humans), birds, reptiles and amphibians.

Many of the Gammaretroviruses share a conserved RNA structural element called a core encapsidation signal.

One gammaretrovirus, Xenotropic murine leukemia virus-related virus (XMRV), is a recombinant virus created in a laboratory accident in the mid-1990s. It is known to infect human tissue, but no known disease is associated with the infection.

The avian reticuloendotheliosis viruses (REVs) are not strictly avian viruses - it now appears that REVs are mammalian viruses that were accidentally introduced into birds in the 1930s during research on malaria.



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