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Fungal mating pheromone receptors

Fungal pheromone mating factor STE2 GPCR
PDB 1pjd EBI.jpg
Structure of a Peptide Segment of the 6th Transmembrane Domain of the Saccharomyces cerevisiae alpha-Factor Receptor.
Identifiers
Symbol STE2
Pfam PF02116
InterPro IPR000366
SCOP 1pjd
SUPERFAMILY 1pjd
OPM superfamily 6
OPM protein 2k9p

Fungal pheromone mating factor receptors form a distinct family of G-protein-coupled receptors.

Mating factor receptors STE2 and STE3 are integral membrane proteins that may be involved in the response to mating factors on the cell membrane. The amino acid sequences of both receptors contain high proportions of hydrophobic residues grouped into 7 domains, in a manner reminiscent of the rhodopsins and other receptors believed to interact with G-proteins.



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