The Fry family is not one unitary genealogical entity, but rather many separate (often prominent) families with distinct genetic profiles and geographic origins.
One such distinct Fry Family was prominent in England, especially Bristol, in the Society of Friends, and in the confectionery/Chocolate business in the 18th, 19th, and early 20th centuries, described at Fry family (chocolate).
Another prominent Fry family (with ties to Dorset, England) is that associated with Col. Joshua Fry of US Revolutionary War fame. This family has been zealously documented for its many contributions to the founding of the United States (e.g., the commissioning of George Washington as commander), its role in the histories of Washington, D.C., Virginia, Tennessee and Kentucky, as well as in the establishment of institutions of higher learning. Although well-documented, there are many misconceptions regarding the descendants of Col. Joshua Fry. In recent years, advanced genealogical work and genetic testing have dispelled some of these misconceptions
Henrich Frey (b. about 1660 in Alsace, Germany) is considered the progenitor of another notable Fry family in the United States. Having arrived in Pennsylvania around 1685, Heinrich Frey and his family is credited with holding the first charter for the land that became Philadelphia and building what is considered today the historical "Old Town" section of that city. The Heinrich Frey Family Association is dedicated to promoting genealogical research and fostering connections between the descendants of Heinrich Frey (which are thought to include, among many others, Nicolas "Fry" Charney founder of Psychology Today and Bill Haslam, 49th Governor of Tennessee).
The name Fry has many spelling variations including Frey, Frye and Frei, all of which probably started out as a designation for someone who was free (i.e., not a serf and not belonging to a lord). The Old English root frig, meaning "free born", is associated with the name. Thus, anyone earning their freedom or who wished to be known for their free-born status, was potentially known by that name. Although the traditional no "e" spelling of Fry is typically associated with any number of British, Fry lines, it is by no means exclusive to those lines (particularly in the United States where genetically distinct Fry lines of British, Swiss, and Germanic origins have been identified). In Britain, the earliest records of this surname appear mainly in the west country. Thomas le Frye, recorded in the Wiltshire rolls of 1273 and the Malmesbury region of North Wiltshire, provides one such example.