Francisco Ramírez, also known as "Pancho" Ramírez as well as "El Supremo Entrerriano" (1786 – 1821), was an Argentine governor of Entre Ríos during the Argentine War of Independence
Francisco Ramírez was born at Concepción del Uruguay in 1786. The son of a Paraguayan merchant and a half-brother of Ricardo López Jordán, he achieved fame when young in the military of his birth town.
He joined the patriots in 1810, working with Díaz Vélez and Rondeau. At the outbreak of the May Revolution he served in the patriot army. In October 1811, the town's soldiers recaptured it for the patriots, directed by Ramírez among others.
He acquired a certain notoriety for fighting alongside the federal leader José Gervasio Artigas with Ricardo López Jordán. They fought in the Banda Oriental against the Royalists.
Faithful to Artigas, when the Buenos Aires Director declared his opposition to Artigas, Ramírez defended him, fighting under Eusebio Hereñú, Artigas' deputy in the region. After the defeat of the Baron von Holmberg, the commander of the centralist side, Ramírez joined Hereñú to defend the Banda Oriental against the Portuguese invasions. The Banda Oriental was finally conquered by the Empire of Brazil. Ramírez and Hereñú also took Santa Fe Province in alliance with Estanislao López.
Once governor of Entre Ríos, Ramírez allied with Estanislao López, from Santa Fe, against Buenos Aires. The Supreme Director Juan Martín de Pueyrredón attempted a conciliatory policy and made a pact with Hereñú to reincorporate Entre Ríos into the Buenos Aires faction. Ramírez took arms against Hereñú and defeated him in 1817. He was in charge of the Uruguay River region as a deputy for Artigas. The Paraná River and La Bajada region were officially in the hands of other men, but in practice they were run by Ramírez.