Francisco Malespín Herrera (1806 – 25 November 1846) was an army officer and politicians, elected as the president of El Salvador in 1844. He served from 7 February 1844 to 15 February 1845, when he was deposed by his vice president Joaquín Eufrasio Guzmán after leading the country to war against Guatemala, a neighboring state of the Federal Republic of Central America. After being deposed, Malespin returned to El Salvador with forces from Honduras, but he was captured and assassinated.