Francisco José Domingo y Marqués (12 March 1842, Valencia – 22 July 1920, Madrid) was a Spanish painter in the Eclectic style.
He began his studies at the Real Academia de Bellas Artes de San Carlos, where he was a student of Rafael Montesinos y Ramiro (1811-1874/77), a great admirer of José de Ribera, whose works Domingo copied as his first exercises. In 1864, he moved to Madrid to continue his studies at the Real Academia de Bellas Artes de San Fernando with Federico de Madrazo. Three years later, he was awarded a pension by the "Diputación Provincial de Valencia" (the local government) to continue his studies in Rome. He went there in 1868, where he obtained a position in the workshop of Eduardo Rosales.
While there, he sent his works to the National Exhibition of Fine Arts, winning several awards for his Baroque-style paintings. Suffering from the effects of malarial fever, he returned to Spain and taught at the Academia de San Carlos for a year. His portrait of Santa Clara praying won First Prize at the Exhibition of 1871. That same year, his pension was cancelled, as he showed no inclination to return to Rome. As a result, he moved to Madrid, where he found work decorating various buildings, including the palace of Eduardo, Duque de Bailén.
He married in 1874 and, the following year, moved to Paris, where his works consisted largely of detailed historical genre scenes and portraits for high society patrons, many of whom were former clients of Marià Fortuny. During this time, he absorbed some elements from the style of Meissonier as well as brightening his palette under the influence of the Impressionists. He also made contacts with art dealers in the United States. William Henry Vanderbilt and Augustin Daly were among those who bought his paintings.