Francis West (28 October 1586 – February 1633/1634) was a Deputy Governor of the Colony and Dominion of Virginia.
West was the second son of Thomas West, 2nd Baron De La Warr (1556–1602) of Wherwell Abbey in Hampshire and his wife, Anne Knollys, and was born in Salisbury, Wiltshire on 28 October 1586.
West was one of four brothers. His elder brother, Thomas West, 3rd Baron De La Warr (1577–1618), served as a governor of the Virginia Company of London from 1610-1611. His younger brother, Governor John West (1590-ca 1659), served as Crown Governor of Virginia from 1635-1637. A fourth brother, Nathaniel West, died in Virginia in August 1623, aged 30.
As Captain, he arrived at Jamestown, Virginia, in July 1608; He was elected to the Governor's Council in 1608, and returned there on the Mary Ann Margett in 1610. From 1612 to 1617 he was the Commandant of Jamestown. From July 30 through August 4, 1619, he served as an appointed representative in Jamestown's first Legislative Assembly. This was the first House of Burgesses appointed by Governor Sir George Yeardley. In 1622 he was appointed Admiral to New England, where he served alongside Capt. Christopher Levett, Governor of Plymouth, on a three-man council under Capt. Robert Gorges, named Governor General of the Plymouth Council for New England's venture in Massachusetts. West subsequently served as Deputy Governor of Virginia from 17 November 1627 to 5 March 1629. He also served as Captain General of Virginia.