Francesco Maria Marescotti, Principe Ruspoli (March 5, 1672 – Rome, July 14, 1731) was the ?th Marchese and 1st Principe di Cerveteri, 1st Marchese di Riano and 6th Conte di Vignanello.
He was a son of Alessandro Marescotti, 5th Conte di Vignanello and first wife Anna Maria dei Marchesi Corsini.
Also he was a paternal grandson of Sforza Vicino Marescotti, 4th Conte di Vignanello and wife Vittoria dei Principi Ruspoli dei Marchesi di Cerveteri (? – Rome, February 11, 1681).
His son was Bartolomeo Ruspoli.
He married Isabella Cesi dei Duchi di Acquasparta (1676 – November 10, 1753), maternal niece of Pope Innocent XIII, by whom he had nine children: