François Joseph Lestiboudois (20 January 1759 – 26 July 1815) was a French botanist. Born at Lille, he was the son of Jean-Baptiste Lestiboudois (1715–1804), a professor of botany at the École centrale du département du Nord à Lille and was the father of botanist (1797–1876).
Lestiboudois was a professor of botany at Lille and a member of the Société des sciences, de l'agriculture et des arts de Lille. He is best remembered for publication of Botanographie belgique (first edition in 1781). He was also the author of Botanographie universelle, ou, Tableau général des végétaux (1804). He died in Lille in 1815.