Fornix of brain

Fornix
Diagram of the fornix. Right=anterior
Fornix of the mouse brain
Details
Artery	Small medial central branches of the anterior communicating artery
Identifiers
Latin	Fornix
MeSH	A08.186.211.577.265
NeuroNames	hier-250
NeuroLex ID	Fornix
TA	A14.1.08.949 A14.1.09.255
FMA	61965
Anatomical terms of neuroanatomy []

The fornix (Latin: arch) is a C-shaped bundle of nerve fibers in the brain that acts as the major output tract of the hippocampus. The fornix also carries some afferent fibres to the hippocampus from structures in the diencephalon and basal forebrain. The fornix is part of the limbic system. While its exact function and importance in the physiology of the brain is still not entirely clear, it has been demonstrated in humans that surgical transection – the cutting of the fornix along its body – can cause memory loss. There is some debate over what type of memory is affected by this damage, but it has been found to most closely correlate with recall memory rather than recognition memory. This means that damage to the fornix can cause difficulty in recalling long-term information such as details of past events, but it has little effect on the ability to recognize objects or familiar situations.

The fibers begin in the hippocampus on each side of the brain as fimbriae; the separate left and right sides are each called the crus of the fornix (plural crura). The bundles of fibers come together in the midline of the brain, forming the body of the fornix. The lower edge of the septum pellucidum (the membrane that separates the lateral ventricles) is attached to the upper face of the fornix body.

The body of the fornix travels anteriorly and divides again near the anterior commissure. The left and right parts separate, but there is also an anterior/posterior divergence.

The lateral portions of the body of the fornix are joined by a thin triangular lamina, named the psalterium (lyra). This lamina contains some commissural fibers that connect the two hippocampi across the middle line and constitute the commissure of fornix (also called the hippocampal commissure).