The Floyd Landis doping case is a doping scandal that featured Floyd Landis, the initial winner of the 2006 Tour de France. After a meltdown in Stage 16, where he had lost ten minutes, Landis came back in Stage 17 riding solo and passing his whole team. However, a urine sample taken from Landis immediately after his Stage 17 win has twice tested positive for banned synthetic testosterone as well as a ratio of testosterone to epitestosterone nearly three times the limit allowed by World Anti-Doping Agency rules. The International Cycling Union stripped him of his 2006 Tour de France title. Second place finisher Óscar Pereiro was officially declared the winner. The only previous Tour de France winner to be disqualified was 1904 Tour de France winner Maurice Garin.
Landis was wearing the maillot jaune prior to Stage 16, but then lost eight minutes and seemed finished. However, Landis spectacularly came back in Stage 17, winning the stage and cutting his deficit to leader Óscar Pereiro to half a minute. Overtaking him after the Stage 19 time trial, Landis was celebrated as the winner of the 2006 Tour de France.
On July 27, 2006, four days after the Tour had finished, the Phonak Cycling Team announced Floyd Landis had a urine test come back positive, having an unusually high ratio of the hormone testosterone to the hormone epitestosterone (T/E ratio) after the epic performance in Stage 17. Landis denied having doped and placed faith in a test using his backup sample. Phonak stated that he would be dismissed should the backup sample also test positive. It did, and Landis was suspended from professional cycling and dismissed from his team. Landis's personal physician Arnie Baker later disclosed that the test had found a T/E ratio of first 12:1, later 11:1, in Landis, far above the maximum allowable ratio of 4:1. The test on Landis's Stage 17 A sample had been performed by the French government's anti-doping clinical laboratory, the National Laboratory for Doping Detection (LNDD). LNDD is a division of the Ministry of Youth, Sport, and Social Life and is accredited by WADA, the World Anti-Doping Agency. The B sample confirmed the A sample, and also tested positive for an unnatural source of testosterone.