The Flemish chapel (Spanish: capilla flamenca) was one of two choirs employed by Philip II of Spain, the other being the Spanish chapel (or capilla española).
Philip I of Castile, "Philip the Handsome", son of Maximilian I, Holy Roman Emperor and Mary of Burgundy, enlarged the Grande Chapelle in the Netherlands whose members included Alexander Agricola and Pierre de La Rue. Following his marriage to Juana of Castile (1496) the chapel accompanied him to the summit in Toledo, Spain in 1502 and again to Spain in 1505 where he died suddenly at Burgos in 1506, though was not buried for three years until his widow Juana "the mad" was committed to an asylum in 1508, when the Grand Chapelle, or capilla, returned to Brussels.
Philip's sister Archduchess Margaret of Austria became regent for the infant Charles V, and she reestablished the Burgundian musical establishment at Mechelen, with the composers Antoine Brumel, Pierre de La Rue, Antoine de Longueval, and Pierrequin de Thérache and Marbrianus de Orto as director of the court chapel, la Grand Chapelle. Margaret ensured a full musical education for her nephew Charles and his older sister Mary of Austria. After Margaret died Charles appointed his sister governor of the Netherlands 1531–1555 at Brussels, where Benedictus Appenzeller was master of the court chapel. Another favourite composer of Margaret was Josquin des Prez.