The First Grinnell Expedition of 1850 was the first American effort, financed by Henry Grinnell, to determine the fate of the lost Franklin Polar Expedition. Led by Lieutenant Edwin De Haven, the team explored the accessible areas along Franklin's proposed route. In coordination with British expeditions, they identified the remains of Franklin's Beechy Island winter camp, providing the first solid clues to Franklin's activities during the winter of 1845 before becoming icebound themselves.
By 1850, three British rescue attempts had already failed to locate Franklin. In April and December 1849, Lady Jane Franklin sent appeals to American President Zachary Taylor that the search continue. When Congress lingered in passing the appropriations to purchase vessels, American merchant Henry Grinnell purchased two brigs, the 91-ton Rescue and 144-ton Advance, refitted them for arctic service and offered them to the government, who quickly provided additional funds and volunteer Naval officers and crew The expedition was instructed to focus on the areas of Wellington Channel and Cape Walker as conditions permitted. Dr. Elisha Kent Kane was brought in from field work in Florida to serve as surgeon aboard the Advance. Preparation was managed quickly, and the expedition set out on May 22, 1850 from the Navy Yard at New York.
Sighting Greenland on June 20, the expedition made harbor at the Crown Prince Islands (Whale Fish) in Disco Bay. From a British mail ship, they learned that British relief efforts were heading for the same region. Advance and Rescue left the islands on June 29, encountering the ice field on July 1 while proceeding towards Upernavik. By July 7, the pack ice was dense enough to compel the Advance to tow the Rescue to prevent the vessels from becoming separated. The crews were periodically sent onto the ice to 'bore' a passage by hand, using crowbars, ice anchors and boathooks. For 21 days the ships were held nearly fast, only heaved slowly forward by efforts of the crew.