The First Battle of Middlewich took place on 13 March 1643, during the English Civil War, and was fought between the Parliamentarians, under Sir William Brereton, and the Royalist supporters of King Charles I of England, under Sir Thomas Aston.
In the summer of 1642 came the final split between the King and Parliament and both sides made preparations for raising an army. Throughout the summer Commissioners of Array for the King and Deputy Lieutenants for Parliament attempted to raise the trained bands and to seize the in every county. During the confusion caused by the troops waiting to be shipped from Chester to Ireland to suppress the rebellion there, Sir William Brereton, the Parliamentary representative in Cheshire, turned to what was virtually recruiting. He found himself opposed by Sir Thomas Aston and all the resident Cheshire nobility and he failed in his attempt to secure Chester for Parliament.
At this time Aston was probably the recognized representative of the King in the county and was able to present the latter with a list of men willing to serve in the King's army. The King decided to base this army at Shrewsbury and when he arrived there on 20 September 1642 he wrote to Lord Kilmorey, Lord Cholmondeley and "the other of the subscribers for Horse in Cheshire" telling them to deliver their horses into the charge of Aston who was to bring the forces raised to Shrewsbury to join with the main body of the army. Charles made it unnecessary for Aston to leave for Shrewsbury as he instead came to Chester and it was from here that he issued, on 26 September, an order for the seizure of arms and horses from those people who had carried out Parliament's Militia Ordinance in Cheshire. These were to be delivered to Aston who was able to leave with the King at the head of three troops of horse.