Filtration slits
| Podocyte | |||
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Renal corpuscle structure
Blood flows in the afferent arteriole (9) at the top, and out the efferent arteriole (11) at the bottom. Blood flows through the capillaries of the glomerulus (10), where it is filtered by pressure. The podocytes (3a and 3b, green) are wrapped around the capillaries. Blood is filtered through the slit diaphragm (or filtration slit), between the feet or processes of the podocytes. The filtered blood passes out the proximal tubule (B, yellow) on the right.
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| Details | |||
| Precursor | Intermediate mesoderm | ||
| Latin | podocytus | ||
| Dorlands /Elsevier |
Podocyte | ||
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Anatomical terminology
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Blood flows in the afferent arteriole (9) at the top, and out the efferent arteriole (11) at the bottom. Blood flows through the capillaries of the glomerulus (10), where it is filtered by pressure. The podocytes (3a and 3b, green) are wrapped around the capillaries. Blood is filtered through the slit diaphragm (or filtration slit), between the feet or processes of the podocytes. The filtered blood passes out the proximal tubule (B, yellow) on the right.
A - Renal corpuscle
B - Proximal tubule
C - Distal convoluted tubule
D - Juxtaglomerular apparatus
1. Basement membrane (Basal lamina)
2. Bowman's capsule - layer
3. Bowman's capsule - visceral layer
3a. Pedicels (podocyte processes)
3b. Podocyte
4. Bowman's space (urinary space)
5a. Mesangium - Intraglomerular cell
5b. Mesangium - Extraglomerular cell
6. Granular cells (Juxtaglomerular cells)
7. Macula densa
8. Myocytes (smooth muscle)
9. Afferent arteriole
10. Glomerulus capillaries
11. Efferent arteriole
Podocytes are cells in the Bowman's capsule in the kidneys that wrap around capillaries of the glomerulus. The Bowman's capsule filters the blood, retaining large molecules such as proteins while smaller molecules such as water, salts, and sugars are filtered as the first step in the formation of urine. Although various viscera have epithelial layers, the name visceral epithelial cells usually refers specifically to podocytes, which are specialized epithelial cells that reside in the visceral layer of the capsule.
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