Feline hyperesthesia syndrome, also known as rolling skin disease, is a rare illness in domestic cats that causes episodes of agitation, self-mutilation, and a characteristic rippling of the skin when touched. It is often described as a seizure disorder but the cause is unknown.
During an episode cats show a number of typical signs, including skin rolling or twitching, compulsive self-grooming, self-directed pouncing, or aggressive behaviour such as biting or attacking the tail. There may also be pupil dilation, vocalisation and a general increase in activity.
The cause of feline hyperesthesia syndrome is unknown. Some experts believe FHS to be a form of epilepsy, while others believe it is a behavioural disorder triggered by trauma. Noting that affected cats tend to be dominating rather than submissive, some research argues that FHS is conflict displacement in which the cat acts out thwarted territorial disputes on its own body.
Although any age, breed, or sex of cat can develop feline hyperesthesia syndrome, those most susceptible include the Siamese, Burmese, and Himalayan breeds.
Treatment includes anti-anxiety medication, anti-depressants such as SSRIs, or sedatives.