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Exonuclease VII

Exonuclease VII, large subunit
Identifiers
Symbol Exonuc_VII_L
Pfam PF02601
InterPro IPR020579
Exonuclease VII small subunit
PDB 1vp7 EBI.jpg
crystal structure of exodeoxyribonuclease vii small subunit (np_881400.1) from bordetella pertussis at 2.40 a resolution
Identifiers
Symbol Exonuc_VII_S
Pfam PF02609
InterPro IPR003761

In molecular biology, exonuclease VII (EC 3.1.11.6, Escherichia coli exonuclease VII, E. coli exonuclease VII, endodeoxyribonuclease VII, Exodeoxyribonuclease VII) is a bacterial exonuclease enzyme. It is composed of two nonidentical subunits; one large subunit and 4 small ones. Exonuclease VII catalyses exonucleolytic cleavage in either 5'-3' or 3'-5' direction to yield 5'-phosphomononucleotides. The large subunit also contains an N-terminal OB-fold domain that binds to nucleic acids.

This article incorporates text from the public domain Pfam and InterPro IPR020579

This article incorporates text from the public domain Pfam and InterPro IPR003761


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