Eusebius of Nicomedia (died 341) was the man who baptised Constantine the Great. He was a bishop of Berytus (modern-day Beirut) in Phoenicia, then of the See of Nicomedia, where the imperial court resided, and finally of Constantinople from 338 up to his death.
Distantly related to the imperial family of Constantine, he owed his progression from a less significant Levantine bishopric to the most important episcopal see to his influence at court, and the great power he wielded in the Church was derived from that source. In fact, during his time in the Imperial court, the Eastern court and the major positions in the Eastern Church were held by Arians or Arian sympathizers. With the exception of a short period of eclipse, he enjoyed the confidence both of Constantine and Constantius II. He also served as the tutor of the later Emperor Julian the Apostate; and it was he who baptized Constantine the Great on May 22, 337 owing to his familial relationship with the emperor. Also during his time in the Imperial court, Arianism became more popular with the Royal family. It can be logically surmised that Eusebius had a huge hand in the acceptance of Arianism in the Constantinian household. The Arian influence grew so strong during his tenure in the Imperial court that it wasn't until the end of the Constantinian dynasty and the appointment of Theodosius I that Arianism lost its influence in the Empire.
It was of particular interest that Eusebius was nearly persecuted because of his close relationship to the Emperor Licinius while serving as Bishop of Nicomedia during Licinius' reign.