Emmanuel Drake del Castillo (28 December 1855 – 14 May 1904) was a French botanist.
He was born at Paris and studied with Louis Édouard Bureau (1830–1918) at the Muséum national d'histoire naturelle (National Museum of Natural History). Between 1886 and 1892, he published Illustrationes Florae Insulae Maris Pacifici ("Illustrations of the flora of the islands of the Pacific Ocean") a summarization of his work on the flora of French Polynesia. He also studied the flora of Madagascar.
In addition, he put together a herbarium which contained more than 500,000 samples. He died in 1904 at Saint-Cyran-du-Jambot, bequeathing his herbarium to the Muséum national d'histoire naturelle.
He was the taxonomic authority of numerous plants. The following is a list of botanical genera that he described: