Sir Edward Williams (1659–1721) was an English politician who sat in the House of Commons for the Welsh constituency of Breconshire.
Williams was the second son of Sir Thomas Williams who was the royal physician to King Charles II. He was baptised at Elham, Kent on 6 November 1659. By 1675 he had already been knighted and was married on 9 July of that year to Elizabeth, the daughter and coheir of Sir Henry Williams. This marriage brought him a modest estate in Breconshire, a county he would represent in Parliament for seventeen years.
Edward and Elizabeth had four children:.
Sir Edward died on 28 July 1721, and was buried at Aberllynfi.