Edward Topham (1751–1820) was an English journalist and playwright.
He was the son of Francis Topham, LL.D. (d. 15 October 1770), Master of Faculties and judge of the Prerogative Court at York, whose feud with Dean Fountayne was lampooned by Laurence Sterne in The History of a Warm Watch Coat.
Edward was educated at Eton College under Dr. John Foster (1731–1774), and remained there for eleven years. While at school he dabbled in poetry and was one of the leaders in the rebellion against Foster's rule. He was admitted at Trinity College, Cambridge, as pensioner on 22 April 1767, and as fellow-commoner on 23 October 1769, but he left without taking a degree. On leaving the university, Topham travelled on the continent and spent six months in Scotland, publishing upon his return in 1776 a volume of Letters from Edinburgh, 1774 and 1775, containing some Observations on the Diversions, Customs, Manners, and Laws of the Scotch Nation. He next came to London and purchased a commission in the First Regiment of Lifeguards. By 1777 he was "cornet of his majesty's second Troop of Horse-guards", and for about seven years he was the adjutant. He brought his regiment to a high state of efficiency, for which he received the thanks of the King and figured in the press as "the tip-top adjutant".
Topham soon became known in the fashionable world of London for his original style of dress and the ease and elegance of his manners. His personal and sartorial peculiarities were copied by his friend Frederic Reynolds to enliven the characters in his comedies. Meanwhile, Topham's talent as a writer of prologues and epilogues introduced him to the leading actors of the day, and led to his first appearance as a playwright. An epilogue, spoken by Charles Lee Lewes in imitation of a Molière character, filled Drury Lane for several nights. Another, on a recent tragedy, spoken by Miss Farren, was equally popular. He wrote an epilogue for the benefit of Mary Wells, and their friendship soon became intimacy. They lived together for several years, and four children resulted from the union.