Sir Edward Rodes (c. 1600 – 19 February 1666), of Great Houghton, Yorkshire, served as sheriff of Yorkshire and colonel of horse under Cromwell; he was also a member of Cromwell's privy council, sheriff of Perthshire, and represented Perth in the parliaments of 1656-8 and 1659-1660. Sir Edward's sister Elizabeth was third wife and widow of Thomas Wentworth, 1st Earl of Strafford.
Notwithstanding the near connection which subsisted between Sir Edward Rodes and the Earl of Stratford (his sister Elizabeth was Stafford's third wife and widow), there was a wide difference in the political and religious views of each. Few entered more eagerly into the objects contemplated by the Long Parliament, when affairs were advancing to a crisis; and it was for the most part to Sir Edward Rodes, and his two friends the Hothams, that the scheme, for maintaining the peace of Yorkshire (the Treaty of Neutrality), arranged by the two great parties at Rothwell on 29 September, before the war began, was frustrated. Sir Edward's zeal that may have be quickened by personal injury—One of the stipulations at the treaty was that reparation should be made to "Sir Edward Rodes for the injury done him"—for at the beginning of September, 1643, an attack was made on his house at Great Houghton, by a party of royalists under the command of Captain Grey, when, according to the of the time, all the outhouses were burnt, his goods plundered to the amount of £600, his lady uncivilly treated, some of his servants wounded, and one slain.
Of all the gentry of Yorkshire, there were only two dissenters, on the parliament side, to that engagement of neutrality, young Holham and Sir Edward Rhodes who, although of better quality, was not so much known or considered as the other; but they quickly found seconds enough when the parliament refused to ratify the treaty, and declared it to be injurious to the common cause.
Later during the First Civil War Rodes was taken into custody by Parliament, and with the Hothams committed to the Tower of London, but as nothing could be proved against him he was liberated, (Sir John Hotham and his son, John Hotham the younger, were beheaded for treason after they were found guilty of conspiring to hand Hull over the Royalists).