Eduard Wölfflin (1 January 1831, Basel – 8 November 1908, Basel) was a Swiss classical philologist. He was the father of art historian Heinrich Wölfflin (1864–1945).
From 1848 to 1854, he studied at the Universities of Basel and Göttingen, where he was a pupil of Karl Friedrich Hermann. Following graduation, he worked as an assistant librarian at the University of Basel (1854–61).
He spent the next decade as schoolteacher in Winterthur (1861–71), and in the meantime became an associate professor in Latin philology (1869). In 1871 he attained a full professorship at the University of Zurich. From 1875 to 1880, he was a professor at the University of Erlangen, and from 1880 to 1906, was a professor at the University of Munich. Wölfflin was a member of the Bavarian Maximilian Order for Science and Art.
He was a primary catalyst in the establishment of the Thesaurus Linguae Latinae, a comprehensive dictionary of the Latin language — a project that first got underway in 1894. He was also editor of the Archiv für latinische Lexikographie und Grammatik (from 1884), a periodical that grown to 15 volumes at the time of Wölfflin's death in 1908. Other significant writings by Wölfflin include: