Edmund Isham D.D. (1744?–1817) was an academic administrator at the University of Oxford.
Isham was elected Warden (head) of All Souls College, Oxford in 1793, a post he held until his death in 1817. While Warden at All Souls College, Isham was also Vice-Chancellor of Oxford University from 1797 until 1798.
A portrait of Ishman was painted by William Owen (1769–1825) and a mezzotint engraving was produced by Samuel William Reynolds (1773–1835) in 1810.