Jean Octave Edmond Perrier (9 May 1844 – 31 July 1921) was a French zoologist born in Tulle. He is known for his studies of invertebrates (annelids and echinoderms). He was the brother of zoologist Rémy Perrier (1861–1936).
On advice from Louis Pasteur, he studied sciences at the École Normale Supérieure, where he took classes in zoology from Henri de Lacaze-Duthiers (1821–1901). Afterwards he was a schoolteacher for three years at the college in Agen. In 1869 he obtained his doctorate in natural sciences, later replacing Lacaze-Duthiers at the École normale supérieure (1872).
In 1876 he attained the chair of Natural History (mollusks, worms and zoophytes) at the Muséum national d'histoire naturelle, and in 1879 became chairman of the Société zoologique de France. In the early 1880s he participated in a series of sea expeditions, during which, he performed investigations of marine life located within the benthic zone, subsequently gaining international recognition as a specialist of marine fauna.
In 1892 he became a member of the Académie des sciences, and even though he wasn't a doctor of medicine, he became a member of the Académie nationale de médecine (1898). From 1900 to 1919 he was director of the museum of natural history, where during the same time period (1903), he succeeded Henri Filhol (1843–1902) as chair of comparative anatomy.