Dunn Human Nutrition Unit
The Wellcome Trust/MRC building, housing the Cambridge Institute for Medical Research and the MRC Mitochondrial Biology Unit
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| Abbreviation | MBU |
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| Formation | 1927 |
| Type | Research institute |
| Legal status | Government agency |
| Purpose | research |
| Headquarters | The Wellcome Trust/MRC building |
| Location |
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Director
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Professor Massimo Zeviani |
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Parent organization
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Medical Research Council |
| Website | MBU |
The MRC Mitochondrial Biology Unit (formerly the MRC Dunn Human Nutrition Unit) is an institution of the Medical Research Council based at the Addenbrooke’s Hospital / Cambridge Biomedical Campus site in Cambridge, England. The unit is a University of Cambridge partner institution concerned with the study of the , as this organelle has a varied and critical role in many aspects of eukaryotic metabolism and is implicated in a large number of metabolic, degenerative, and age-related human diseases.
The Unit was originally founded in 1927 using a donation from Sir William Dunn, who left £1 million to charity on his death in 1912. Part of this money was used to fund what was then called the Dunn Nutritional Laboratory, with its research supported by the MRC. The Unit was renamed in 2009 to the Mitochondrial Biology Unit under the directorship of Professor Sir John Walker to reflect its expertise in mitochondrial research. The current director of the Unit is Professor Massimo Zeviani.
The Unit has three major scientific aims:
The MBU is organised into eleven independent research groups and includes 30-40 graduate students who are members of the University of Cambridge:
The MBU is the home of several freely-accessible scientific web-resources:
MitoMiner - a mitochondrial proteomics database that provides information on cellular localisation, function and species & tissue specific expression
The Integrated Mitochondrial Protein Index (IMPI) - a list of all the genes and proteins that make up the mammalian mitochondrion
Professor Massimo Zeviani (2013 - )
Professor Sir John Walker (1998 - 2013)
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